rabbit anti phospho iκbα Search Results


rabbit monoclonal antibody against nf κb p65  (Bioworld Antibodies)
90
Bioworld Antibodies rabbit monoclonal antibody against nf κb p65
Effects of artemisinin on the nuclear translocation of nuclear factor‐kappa B <t>(NF‐κB)</t> <t>p65</t> in APPswe/PS1dE9 double transgenic mice. Brain tissues from APPswe/PS1dE9 mice were subjected to immunohistochemistry to determine the nuclear translocation of NF‐κB p65. (A) Representative photographs of immunohistochemistry <t>staining</t> <t>with</t> <t>anti‐NF‐κB</t> p65 antibody (with 200× magnification). (B) Representative photographs of immunohistochemistry staining with anti‐NF‐κB p65 antibody (with 400× magnification). Artemisinin significantly reduced the ratio of NF‐κB p65 nuclear–positive cells. Black arrows point to NF‐κB p65 nuclear–positive cells. Bars: 50 μm. (C) Quantification of the ratio of NF‐κB p65 nuclear–positive cells in APPswe/PS1dE9 mice in each group; the numbers represent the mean ± SEM. n = 3 mice each. *P < 0.05 by Student's t‐test.
Rabbit Monoclonal Antibody Against Nf κb P65, supplied by Bioworld Antibodies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rabbit+anti+phospho+i%CE%BAb%CE%B1/pmc06493386-109-68-75?v=Bioworld+Antibodies
Average 90 stars, based on 1 article reviews
rabbit monoclonal antibody against nf κb p65 - by Bioz Stars, 2026-07
90/100 stars
  Buy from Supplier
rabbit anti-phospho-iκbα-s32/36 antibody  (RayBiotech)
N/A
Phospho-I?B?-S32/36 Polyclonal Antibody
   Buy from Supplier

Image Search Results


Effects of artemisinin on the nuclear translocation of nuclear factor‐kappa B (NF‐κB) p65 in APPswe/PS1dE9 double transgenic mice. Brain tissues from APPswe/PS1dE9 mice were subjected to immunohistochemistry to determine the nuclear translocation of NF‐κB p65. (A) Representative photographs of immunohistochemistry staining with anti‐NF‐κB p65 antibody (with 200× magnification). (B) Representative photographs of immunohistochemistry staining with anti‐NF‐κB p65 antibody (with 400× magnification). Artemisinin significantly reduced the ratio of NF‐κB p65 nuclear–positive cells. Black arrows point to NF‐κB p65 nuclear–positive cells. Bars: 50 μm. (C) Quantification of the ratio of NF‐κB p65 nuclear–positive cells in APPswe/PS1dE9 mice in each group; the numbers represent the mean ± SEM. n = 3 mice each. *P < 0.05 by Student's t‐test.

Journal: CNS Neuroscience & Therapeutics

Article Title: Antimalarial Drug Artemisinin Extenuates Amyloidogenesis and Neuroinflammation in APP swe/ PS 1dE9 Transgenic Mice via Inhibition of Nuclear Factor‐κ B and NLRP 3 Inflammasome Activation

doi: 10.1111/cns.12066

Figure Lengend Snippet: Effects of artemisinin on the nuclear translocation of nuclear factor‐kappa B (NF‐κB) p65 in APPswe/PS1dE9 double transgenic mice. Brain tissues from APPswe/PS1dE9 mice were subjected to immunohistochemistry to determine the nuclear translocation of NF‐κB p65. (A) Representative photographs of immunohistochemistry staining with anti‐NF‐κB p65 antibody (with 200× magnification). (B) Representative photographs of immunohistochemistry staining with anti‐NF‐κB p65 antibody (with 400× magnification). Artemisinin significantly reduced the ratio of NF‐κB p65 nuclear–positive cells. Black arrows point to NF‐κB p65 nuclear–positive cells. Bars: 50 μm. (C) Quantification of the ratio of NF‐κB p65 nuclear–positive cells in APPswe/PS1dE9 mice in each group; the numbers represent the mean ± SEM. n = 3 mice each. *P < 0.05 by Student's t‐test.

Article Snippet: The following primary antibodies were used: mouse anti‐LRP1 antibody [5A6] (1:3000; Merck, Darmstadt, Germany), rabbit anti‐RAGE antibody (1:1000; Cell Signaling, Denver, MA, USA), rabbit anti‐APP carboxyl terminal antibody (1:4000; Sigma), rabbit anti‐BACE1 antibody (1:1000; Cell Signaling), rabbit anti‐PS1 antibody (1:1000; Cell Signaling), rabbit anti‐Aph‐1a antibody (1:3000; Invitrogen, Camarillo, CA, USA), rabbit polyclonal antibody against serine 536 phosphorylated NF‐κB p65 (1: 800; Santa Cruz Biotechnology, Santa Cruz, CA, USA), rabbit monoclonal antibody against NF‐κB p65 (1:500; Bioworld Technology), rabbit anti‐IκB‐α antibody (1:1000; Bioworld Technology), rabbit polyclonal antibody against serine 32 phosphorylated IκB‐α (1:1000; Bioworld Technology), rabbit anti‐NALP3 antibody (1:800; Santa Cruz), rabbit anticleaved caspase‐1 (Asp297) (D57A2) antibody (1:1000; Cell Signaling), and mouse anti‐β‐actin antibody (1:1000; Santa Cruz).

Techniques: Translocation Assay, Transgenic Assay, Immunohistochemistry, Staining

Effect of artemisinin on nuclear factor‐kappa B (NF‐κB) activity in APPswe/PS1dE9 double transgenic mice. (A) Brain tissues from APPswe/PS1dE9 mice were subjected to Western blotting to determine the levels of p‐NF‐κB p65, NF‐κB p65, I‐κBα, and p‐I‐κBα, with β‐actin as a loading control. (B) Quantification of p‐NF‐κB p65, NF‐κB p65, I‐κBα, and p‐I‐κBα. Artemisinin significantly decreased the levels of p‐NF‐κB p65, NF‐κB p65, and p‐I‐κBα and increased the level of I‐κBα. n = 3. *, P < 0.05 by Student's t‐test. (C) An ELISA was conducted to measure brain IL‐6 and TNF‐α level in the brains of mice in each group. Artemisinin significantly reduced IL‐6 and TNF‐α level in brains. n = 3. *, P < 0.05 by Student's t‐test.

Journal: CNS Neuroscience & Therapeutics

Article Title: Antimalarial Drug Artemisinin Extenuates Amyloidogenesis and Neuroinflammation in APP swe/ PS 1dE9 Transgenic Mice via Inhibition of Nuclear Factor‐κ B and NLRP 3 Inflammasome Activation

doi: 10.1111/cns.12066

Figure Lengend Snippet: Effect of artemisinin on nuclear factor‐kappa B (NF‐κB) activity in APPswe/PS1dE9 double transgenic mice. (A) Brain tissues from APPswe/PS1dE9 mice were subjected to Western blotting to determine the levels of p‐NF‐κB p65, NF‐κB p65, I‐κBα, and p‐I‐κBα, with β‐actin as a loading control. (B) Quantification of p‐NF‐κB p65, NF‐κB p65, I‐κBα, and p‐I‐κBα. Artemisinin significantly decreased the levels of p‐NF‐κB p65, NF‐κB p65, and p‐I‐κBα and increased the level of I‐κBα. n = 3. *, P < 0.05 by Student's t‐test. (C) An ELISA was conducted to measure brain IL‐6 and TNF‐α level in the brains of mice in each group. Artemisinin significantly reduced IL‐6 and TNF‐α level in brains. n = 3. *, P < 0.05 by Student's t‐test.

Article Snippet: The following primary antibodies were used: mouse anti‐LRP1 antibody [5A6] (1:3000; Merck, Darmstadt, Germany), rabbit anti‐RAGE antibody (1:1000; Cell Signaling, Denver, MA, USA), rabbit anti‐APP carboxyl terminal antibody (1:4000; Sigma), rabbit anti‐BACE1 antibody (1:1000; Cell Signaling), rabbit anti‐PS1 antibody (1:1000; Cell Signaling), rabbit anti‐Aph‐1a antibody (1:3000; Invitrogen, Camarillo, CA, USA), rabbit polyclonal antibody against serine 536 phosphorylated NF‐κB p65 (1: 800; Santa Cruz Biotechnology, Santa Cruz, CA, USA), rabbit monoclonal antibody against NF‐κB p65 (1:500; Bioworld Technology), rabbit anti‐IκB‐α antibody (1:1000; Bioworld Technology), rabbit polyclonal antibody against serine 32 phosphorylated IκB‐α (1:1000; Bioworld Technology), rabbit anti‐NALP3 antibody (1:800; Santa Cruz), rabbit anticleaved caspase‐1 (Asp297) (D57A2) antibody (1:1000; Cell Signaling), and mouse anti‐β‐actin antibody (1:1000; Santa Cruz).

Techniques: Activity Assay, Transgenic Assay, Western Blot, Enzyme-linked Immunosorbent Assay